The Mure Group: Cancer Research
In 2013, it was predicted that 40,000 women in the U.S.A. would die from breast cancer. The majority of these deaths would be caused by breast cancer cells that undergo a transition from non-invasive to invasive and then spread to nearby tissues or even metastasize to other parts of the body. The grim correlation between increased invasiveness and decreased survival highlights the urgent need to identify the biomolecular agents that induce the transition and promote tumor metastasis. The research focus of the Mure Group is to understand the molecular mechanisms whereby the lysyl oxidase family of proteins functions in breast cancer metastasis/invasion. Our ultimate goal is to provide insights that will guide the development of drugs to combat invasive breast cancers.